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Serial ALT measurements estimate liver necrosis in mice

A bioRxiv preprint reports that repeated measurements of circulating alanine aminotransferase, combined with time since acetaminophen exposure, estimated liver necrosis in mice. The method could let researchers follow liver injury in the same animals instead of using separate groups at every timepoint.

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Bio-CM2 Combines Fluorescence and Reflectance in a Miniature Mesoscope

A bioRxiv preprint describes Bio-CM2, a miniature mesoscope combining fluorescence and label-free reflectance imaging across a 7.5 × 10 mm² field of view. Demonstrations in worms, zebrafish and mice paired molecular signals with morphology, behaviour and physiology.