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Khabre desk
Recent reporting, analysis and explainers from the astrocytes desk.
health
A bioRxiv preprint reports that deleting truncated TrkB receptors in astrocytes reduced amyloid plaques and preserved synaptic markers in 5xFAD mice. The findings are from a mouse model, not a human treatment study.
science
A bioRxiv preprint reports higher Serpin A3 levels in human brain tissue from cases with cerebral amyloid angiopathy and Alzheimer’s disease than in neurological controls. The protein was also prominent around damaged vessels in one postmortem case of severe lecanemab-associated ARIA.