health
Preprint Readjudication Finds Avacopan Comparable to Prednisone in Vasculitis
A 2026 readjudication of the 330-person ADVOCATE trial found avacopan produced remission rates similar to a prednisone taper in granulomatosis with polyangiitis and microscopic polyangiitis. The preprint also reports lower glucocorticoid exposure and toxicity with avacopan.