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Khabre desk
Recent reporting, analysis and explainers from the bacteriophages desk.
health
A bioRxiv preprint reports that bacteria sampled from chronic Pseudomonas aeruginosa lung infections in people with cystic fibrosis differed in susceptibility to some bacteriophages. The findings point to variation in bacterial cell-surface features as one possible reason and highlight a challenge for phage therapy.
health
A bioRxiv preprint found that many capsule types in Pakistani carbapenem-resistant Klebsiella pneumoniae genomes have no phage described in the literature. It identifies the South Asian capsule type KL81 as a target for future phage-isolation work.
science
Anthropic says Claude agents identified a previously uncharacterised system in bacteriophages, built around a reverse transcriptase and an array of DNA repeats. Early lab experiments found that the array is expressed as distinct short RNAs; the system’s function is still under investigation.
science
Anthropic says Claude agents identified a previously uncharacterized enzyme system in bacteriophages, built around a known reverse transcriptase and an array of DNA repeats. Early laboratory experiments found that the array is expressed as distinct short RNAs, but the system’s function is still being investigated.
science
A bioRxiv preprint maps bacterial host factors involved in infection by single-stranded RNA and DNA bacteriophages. The study identifies conserved requirements for F-pilus-dependent infection and links an E. coli capsule architecture to selective phage access.