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Study identifies two early progenitor lineages that build the brain

Mouse lineage-tracing experiments and human stem-cell differentiation studies indicate that the developing brain arises from two parallel neural ectoderm progenitors. The finding concerns embryonic cell lineages, not two physically separate adult organs.

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Brain development study finds two progenitor cell populations

Experiments in mouse embryos, human pluripotent stem cells and other species suggest that the brain develops from two distinct progenitor populations. The study also reports an efficient route to hindbrain motor-neuron cells for laboratory disease research.