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Preprint reports workflow to reduce autofluorescence in aged human brain tissue

A bioRxiv preprint reports a Tris-EDTA-supplemented photobleaching workflow that reduced autofluorescence by 58–70% in fresh-frozen aged human brain sections while preserving tissue architecture and cellular content. The study also introduces a 28-plex antibody panel for spatial proteomics.

2026-09-19T04:36:03+05:30
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Adult Mouse Brain Study Finds Gap Junctions on Neuronal Somata

A bioRxiv preprint reports Cx36 gap junctions at direct contacts between neuronal cell bodies in the adult mouse inferior olive. The finding expands the anatomical basis used to model electrical coupling in this brain region beyond dendritic-spine connections.

2026-09-16T14:25:47+05:30