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Khabre desk
Recent reporting, analysis and explainers from the cancer biology desk.
health
A bioRxiv preprint reports that changes involving DNMT1 can reduce CTCF binding at the KMT2A gene and promote copy gains and rearrangements. The findings come from experimental molecular research, not a clinical study.
science
A bioRxiv preprint reports that the protein PBF/PTTG1IP helps coordinate cell adhesion, front–rear polarity and directional movement. The findings come from mouse fibroblasts and human thyroid cancer cells, making them preclinical mechanistic evidence.
science
Researchers at Shandong University and BGI Research describe DiffGSP, a computational framework that models mRNA diffusion to reconstruct spatial gene-expression patterns. The work is a bioRxiv preprint evaluated across diverse spatial-transcriptomics datasets.