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health

Atlas links younger-onset colorectal cancer to a higher stromal share

A single-nucleus atlas of colorectal tumours found a higher stromal-to-epithelial ratio in younger patients with microsatellite-stable cancer. The study also identified age-associated RNA signals and differences in computationally inferred cell communication.

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science

Open model maps tumour-enriched regions in colorectal cancer slides

Researchers at OmiCore have released an openly licensed image-analysis model that marks tumour-enriched regions in colorectal cancer tissue slides. In a preprint, the team reports agreement with transcriptomics on one section and describes limits including its 112 μm resolution and lack of validation across scanners and institutions.