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Khabre desk
Recent reporting, analysis and explainers from the complement-system desk.
health
A bioRxiv preprint reports that mutations tuning complement activity changed how selected monoclonal antibodies protected neonatal mice from lethal HSV-1 infection. The effects varied with the antibody and its viral target.
health
A bioRxiv preprint reports that C3a receptor signalling in leptin-receptor neurons contributes to leptin resistance and obesity-related cardiac changes in mice. Human measurements of complement markers offer an associated finding, not evidence that targeting the pathway treats obesity in people.