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Evidence-first technology, science and health reporting.

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computational-biology

Recent reporting, analysis and explainers from the computational-biology desk.

Representational Khabre illustration for Apple researchers present SimpleDesign, a single-stage multimodal model for jointly designing protein sequences and three-dimensional structures

science

Apple researchers present SimpleDesign, an AI model for joint protein sequence and structure design

Apple researchers describe SimpleDesign, a Transformer-based model that jointly generates protein sequences and three-dimensional structures using a single-stage training approach. The system was trained on more than 2 million sequence–structure pairs, but the supplied evidence reports no experimental validation of its designs.

2026-09-12T11:09:42+05:30
Representational Khabre illustration for AlphaGenome Atlas, a database of predicted molecular effects for human single-nucleotide variants

science

AlphaGenome Atlas catalogs predicted effects of about 9 billion human DNA changes

Google DeepMind says AlphaGenome Atlas pre-calculates predicted molecular effects for approximately 9 billion possible single-nucleotide changes, giving researchers a searchable tool for prioritising variants.

2026-09-09T00:28:23+05:30
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