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science

Open model maps tumour-enriched regions in colorectal cancer slides

Researchers at OmiCore have released an openly licensed image-analysis model that marks tumour-enriched regions in colorectal cancer tissue slides. In a preprint, the team reports agreement with transcriptomics on one section and describes limits including its 112 μm resolution and lack of validation across scanners and institutions.

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health

Preprint maps melanoma immunotherapy response in 2D and 3D

A bioRxiv preprint uses spatial multi-omics and 3D imaging to map melanoma tumours treated with neoadjuvant immunotherapy. The study links organised immune structures, including tertiary lymphoid structures and germinal centres, with treatment response and disease-free survival.