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Khabre desk
Recent reporting, analysis and explainers from the developmental biology desk.
science
Mouse lineage-tracing experiments and human stem-cell differentiation studies indicate that the developing brain arises from two parallel neural ectoderm progenitors. The finding concerns embryonic cell lineages, not two physically separate adult organs.
science
A bioRxiv preprint reports that dermal bone thickens through invading osteoblasts that deposit new mineralised matrix inside older bone. The finding challenges the conventional view that growth relies mainly on bone-forming cells adding matrix at the surface.
science
Experiments in mouse embryos, human pluripotent stem cells and other species suggest that the brain develops from two distinct progenitor populations. The study also reports an efficient route to hindbrain motor-neuron cells for laboratory disease research.
science
A bioRxiv preprint analyses 435 thalidomide-affected limbs and proposes that the unusual order of bone reductions follows the sequential exit of developing bones from a sensitive window.