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Khabre desk
Recent reporting, analysis and explainers from the diagnostics desk.
science
A Purdue University team reports a loop-mediated isothermal amplification assay for detecting Balamuthia mandrillaris. In laboratory testing, the assay detected multiple isolates with higher sensitivity than conventional PCR and produced a visible colour-based result.
health
A medRxiv preprint describes a modified endpoint QuIC assay that detected prion seeding activity in sporadic CJD brain samples within six hours, with some results available in two hours. The assay showed 100% sensitivity and specificity in the reported CSF testing.