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Khabre desk
Recent reporting, analysis and explainers from the epilepsy desk.
health
A bioRxiv preprint reports that an antisense oligonucleotide targeting expanded human ATN1 improved seizure-related outcomes in a humanized mouse model of DRPLA. The findings come from mice, not a human treatment study.
health
Researchers tested a smartphone-based AI platform that let 13 hospitalised adults with epilepsy receive EEG alerts, query personal data and label seizure detections. In simulations, fine-tuning seizure detectors with patient feedback reduced false alarms, but the study was a small inpatient proof of concept.
science
A bioRxiv preprint reports that parvalbumin interneurons and dentate-gyrus changes shape seizure susceptibility in Angelman syndrome model mice. The findings point to altered inhibitory control and homeostatic plasticity as possible drivers of epileptogenesis.