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Khabre desk
Recent reporting, analysis and explainers from the hippocampus desk.
science
A bioRxiv preprint comparing rats with Chinese tree shrews reports that tree-shrew CA1 uses a hybrid spatial code, combining weaker position tuning with more multiplexed neural activity. The findings suggest that spatial representations can change within a conserved hippocampal circuit while retaining core network properties.
science
A bioRxiv preprint combining mathematical modelling with intracellular recordings in behaving mice reports that CA3 pyramidal neurons have an activation exponent slightly above 1, as predicted for stable memory recall. The analysis included 49 new recordings and 133 cells from two earlier studies.
science
A bioRxiv preprint reports a single-neuron correlate of mnemonic pattern separation in the human hippocampus. The finding came from recordings of 3,506 neurons in 97 patients performing a recognition-memory task involving false memories.