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Khabre desk
Recent reporting, analysis and explainers from the innate-immunity desk.
health
A bioRxiv preprint reports that Clec18a dampened inflammatory responses in cell and mouse experiments. The authors propose that it acts through Mincle, TRPM7-dependent calcium entry and the enzyme Cbl.
science
A bioRxiv preprint reports that lysosomal acid lipase helps release cholesterol during phagosome maturation. Inhibiting the enzyme changed membrane organisation and had different effects on the survival of two bacterial pathogens.