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interferon

Recent reporting, analysis and explainers from the interferon desk.

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Preclinical study links neutrophil interferon signalling to anti-PD-1 resistance

A bioRxiv preprint reports that an early interferon-responsive neutrophil program tracked resistance to anti-PD-1 therapy in preclinical models of triple-negative breast cancer. Genetic disruption of interferon signalling in neutrophils improved treatment responses in those models.

2026-10-01T19:25:57+05:30
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Small study links interferon signals to dermatomyositis flares

A six-patient preprint found higher interferon-related gene scores in blood samples associated with dermatomyositis flares. The feasibility study used weekly at-home blood microsampling and RNA sequencing.

2026-09-16T11:08:34+05:30
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