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leukemia

Recent reporting, analysis and explainers from the leukemia desk.

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Machine-learning model reconstructs flow cytometry gates from sample records

A medRxiv preprint presents IMPGAT, a method that infers cell-level flow cytometry gating from sample-level cell-frequency annotations. In leukemia datasets, its reported results were comparable to expert variability in ALL and to a supervised model in AML.

2026-10-22T15:45:18+05:30
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Preprint links DNMT1-driven methylation changes to KMT2A alterations

A bioRxiv preprint reports that changes involving DNMT1 can reduce CTCF binding at the KMT2A gene and promote copy gains and rearrangements. The findings come from experimental molecular research, not a clinical study.

2026-09-23T06:52:30+05:30
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