Science & Technology PublicationEvidence · Explanation · Context
KHABRE.IN

Khabre desk

long-read sequencing

Recent reporting, analysis and explainers from the long-read sequencing desk.

Khabre branded placeholder image

science

LongPhase-TO reconstructs tumour haplotypes from tumour-only DNA

A bioRxiv preprint presents LongPhase-TO, a long-read method for reconstructing somatic haplotypes from tumour samples without matched normal DNA. In tests on eight datasets from six cancer cell lines, the method lengthened haplotype blocks and improved somatic variant-calling scores.

2026-09-20T12:56:12+05:30
Khabre branded placeholder image

science

Preprint presents Isocall for scalable long-read RNA analysis

A bioRxiv preprint describes Isocall, a deterministic method for jointly identifying known and novel transcripts across large PacBio long-read RNA-sequencing datasets. The authors report a joint call across 206 samples in 25 minutes after alignment and profiling.

2026-09-14T11:35:04+05:30