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Hippocampal spike timing carried location and image information beyond firing rates

A bioRxiv preprint reports that the timing of hippocampal neurons’ spikes relative to theta rhythms carried information about locations and viewed images, including in neurons without corresponding firing-rate changes. In human navigation data, spike timing improved location decoding beyond firing rates alone.

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Mouse CA3 neurons match a predicted activation pattern for stable memory recall

A bioRxiv preprint combining mathematical modelling with intracellular recordings in behaving mice reports that CA3 pyramidal neurons have an activation exponent slightly above 1, as predicted for stable memory recall. The analysis included 49 new recordings and 133 cells from two earlier studies.