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Nature Medicine flags image concerns in a 2007 heart study

Nature Medicine has issued an Editorial Expression of Concern over northern blot images in a 2007 paper on microRNA-133 and cardiac hypertrophy. The journal says the original data are no longer available and advises readers to interpret the affected data with caution.

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Preprint presents miRstring for miRNA decoding and artificial RNA design

A bioRxiv preprint describes miRstring, a biogenesis-aware RNA language model trained on 77,708 miRNA precursors from 414 species. The authors report cross-species mature-miRNA boundary decoding and artificial miRNA scaffold designs that repressed target mRNAs in validation experiments.