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Khabre desk
Recent reporting, analysis and explainers from the neurodevelopment desk.
health
A medRxiv preprint reports rare biallelic BECN1 variants in two unrelated families and connects the gene to AMPA-receptor regulation. Mouse and zebrafish experiments support the proposed biological mechanism.
science
A bioRxiv preprint reports that cerebral organoids cultured for more than six months reproduce a pattern of interneuron migration seen in the postnatal human cortex. The researchers used imaging, transcriptomics and gene perturbations to investigate how the cells move and organize.
science
A bioRxiv preprint links autism-associated genes to three molecular programs and to particular neuronal lineages, developmental stages and cortical patterns. The findings come from an integrative analysis of genomic and brain-atlas data.