science
Preprint links PLCXD2 to retinal lipid balance and photoreceptor health
A bioRxiv preprint identifies phosphatidylinositol (PI) as the preferred direct substrate of the enzyme PLCXD2. In a PLCXD2-deficient retinal model, the loss was associated with altered lipid products, synaptic abnormalities, retinal-layer thinning and weaker electrical responses from photoreceptors.