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Lead levels in pregnant women concentrated in greater Dhaka

An analysis of Bangladesh’s 2025 Multiple Indicator Cluster Survey found blood lead at or above 3.5 µg/dL in 17.7% of tested pregnant women, with levels concentrated in greater Dhaka. The medRxiv preprint also found an association between maternal and young-child lead levels.

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Preprint builds a pregnancy register from Greater Manchester care records

A medRxiv preprint describes an algorithm that identified 880,926 pregnancies in Greater Manchester primary-care records. Validation results varied by outcome, with a substantial gap between the register’s miscarriage and termination rates and published UK estimates.

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Mouse preprint identifies neurons required for viable pregnancy

A bioRxiv preprint reports that pregnancy changes gene expression in several hormone-sensitive brain-cell populations in mice. Removing one neuronal type prevented implantation and viable pregnancy in the animals studied.

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Pregnancy risk models performed poorly in large UK validation study

A systematic review and external validation assessed 48 models for predicting four adverse pregnancy outcomes using more than 1.58 million UK pregnancies. Most showed limited discrimination and substantial miscalibration in the UK cohort.