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RNA

Recent reporting, analysis and explainers from the RNA desk.

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A new RNA-design framework uses higher-order interactions to guide sequences

A bioRxiv preprint describes DS3dRNA, a method that scores interactions among groups of RNA structural elements to design sequences for target structures. The authors report improved benchmark performance and experimental activity in designed Mango II and twister RNAs.

2026-09-27T12:36:05+05:30
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Preprint combines protein, RNA and metabolite models for condensate simulations

A bioRxiv preprint presents a physics-based framework that combines protein, nucleic-acid and metabolite models to simulate biomolecular condensates. Its authors report predictions for more than 60 disordered proteins and simulations of RNA- and protein–nucleic-acid condensates.

2026-09-23T13:56:48+05:30
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