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Khabre desk
Recent reporting, analysis and explainers from the SARS-CoV-2 desk.
health
A bioRxiv preprint reports elevated activation in virus-specific CD8 T cells from a subset of people with long COVID. The immune-cell profiles are consistent with persistent antigen stimulation, but provide an indirect signal rather than direct detection of viral antigens.
science
A bioRxiv preprint reports that the host protein HNRNPM binds stem-loop 5 in the SARS-CoV-2 5′-UTR and promotes protein synthesis from the viral RNA. Mutations in the structure’s lower stem reduced both HNRNPM binding and protein synthesis.
science
A bioRxiv preprint describes a transformer model trained on 8.8 million measured SARS-CoV-2 RBD–ACE2 interactions. It predicts receptor-binding compatibility across animal species and pairs predictions with uncertainty estimates to help prioritise surveillance.