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Mouse Spinal-Cord Connectome Maps Two Modes of Sensory Inhibition

A bioRxiv preprint presents a synapse-resolved electron-microscopy dataset of the mouse spinal dorsal horn and a deep-learning tool for classifying sensory neuron types. Its circuit reconstruction identifies inhibitory pathways that preferentially target individual sensory subtypes while also crossing between sensory pathways.

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Mouse Spinal-Cord Study Maps Routes for Touch, Itch, Cold and Pain

A bioRxiv preprint maps how mouse spinal-cord circuits route different sensory signals toward the brain. The wiring diagram distinguishes direct routes for noxious and cooling signals from an interneuron-mediated route for touch and itch.