Search articles by title, topic or section.
Khabre desk
Recent reporting, analysis and explainers from the stem cells desk.
science
Mouse lineage-tracing experiments and human stem-cell differentiation studies indicate that the developing brain arises from two parallel neural ectoderm progenitors. The finding concerns embryonic cell lineages, not two physically separate adult organs.
science
A bioRxiv preprint reports that maintaining 10% oxygen throughout human iPSC-cardiomyocyte differentiation favoured atrial rather than ventricular specification. The laboratory finding could help produce atrial cells but raises process-design concerns for manufacturing ventricular cells.
science
Nature reports extensive cellular integration after human brain tissue was transplanted into mice lacking a cortex. The work could provide a living-animal platform for testing therapies involving human neural tissue.
science
Experiments in mouse embryos, human pluripotent stem cells and other species suggest that the brain develops from two distinct progenitor populations. The study also reports an efficient route to hindbrain motor-neuron cells for laboratory disease research.
science
A bioRxiv preprint describes a human stem-cell-derived nerve-like construct that supported axon regeneration and remyelination in 7-mm sciatic nerve defects in mice.