Brain ageing

Study figure comparing cognitive decline trajectories with human myelin microscopy and axon measurements

science

Dysfunction in the brain's myelin-making cells is linked to age-related cognitive decline

A Nature Medicine study combining human brain tissue with cognitive histories found that worse age-related cognitive decline was associated with abnormal oligodendrocyte and myelin biology, with experimental work implicating reduced NRF2 activity.

2026-09-05T08:20:00+05:30

Kscience

science

Blood-derived immune cells can replace part of the brain's microglial population during ageing

A Nature study using naturally accumulated somatic mutations as lineage markers found evidence that bone-marrow-derived cells enter the ageing human brain and can become a substantial part of the microglial population.

2026-09-05T08:19:00+05:30