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GBD study estimates age-standardized pertussis mortality fell 61%

A Global Burden of Disease analysis estimates that pertussis incidence and age-standardized mortality declined between 1990 and 2023. Its modeled estimates show that the highest population-adjusted mortality risk remained among infants aged 1–5 months.

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Measles cases among children under 5 rebounded to 15.6 million in 2023

A Global Burden of Disease Study estimates that measles cases among children under 5 rose to 15.6 million worldwide in 2023, with 118,000 deaths. The rebound followed years of falling disease burden and coincided with a slight decline in first-dose vaccine coverage.

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Study maps pain across the lifespan in 6.1 million people

Researchers used self-reported data from 6.1 million people in 118 countries to create reference curves for pain across ages 5 to over 100. The estimates show different age patterns by pain site and higher late-life prevalence of several pain types in lower-HDI settings.

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Global medicines regulators urge shift from animal testing

The European Medicines Agency has endorsed an ICMRA statement calling for scientifically valid alternatives to animal testing throughout the human-medicine lifecycle. Regulators also call for tighter justification of animal-based batch-release tests.

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Preprint study links Hib and pneumococcal vaccines to lower global meningitis burden

A longitudinal analysis of 188 countries from 2000 to 2023 found that Hib and pneumococcal conjugate vaccine introduction was associated with lower meningitis disability-adjusted life-year rates. The largest reported association was in the African meningitis belt, although the study describes the results as population-level vaccine-associated changes rather than strictly causal effects.