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Khabre desk
Recent reporting, analysis and explainers from the Neurology desk.
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A man with slowly progressing ALS caused by a rare CHCHD10 mutation showed improved motor-function scores and a biomarker associated with nerve damage returned to the normal reference range one year after receiving a mutation-targeted antisense oligonucleotide treatment.
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A study of 1,065 BCI episodes in ALS patients finds AI agents do not reduce unsafe execution, but a hybrid architecture with an external gate shows promise.
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A medRxiv preprint reports striatal atrophy and increased caudate iron accumulation in asymptomatic female carriers of the genetic variant associated with X-linked dystonia-parkinsonism. The findings came from multimodal MRI in 42 carriers compared with 61 healthy controls.