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Khabre desk
Recent reporting, analysis and explainers from the Cancer Immunotherapy desk.
health
A bioRxiv preprint describes CIDER, a whole-genome sequencing score based on reconstructed T-cell receptor sequences. In patient cohorts, higher scores were associated with better outcomes among people treated with immune checkpoint inhibitors.
health
A bioRxiv preprint reports that an early interferon-responsive neutrophil program tracked resistance to anti-PD-1 therapy in preclinical models of triple-negative breast cancer. Genetic disruption of interferon signalling in neutrophils improved treatment responses in those models.