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Khabre desk
Recent reporting, analysis and explainers from the Cardiovascular Research desk.
health
A bioRxiv preprint reports that activating perivascular thermogenic fat improved aortic stenosis in mice. In human PET-CT scans, thermogenic-fat activity was inversely correlated with measures of disease severity.
health
A bioRxiv preprint reports that BCKDK inhibitors relax blood vessels by antagonising the angiotensin II type 1 receptor (AT1R), independently of BCKDK and branched-chain amino-acid breakdown. The experimental findings raise the possibility that some effects of these inhibitors arise from this separate receptor action.