Search articles by title, topic or section.
Khabre desk
Recent reporting, analysis and explainers from the Genetics desk.
health
A medRxiv preprint analysed gene activity in 1.4 million immune cells from 345 people across 13 Indigenous South American populations. Genetic ancestry was associated with many expression differences, often after immune stimulation.
health
A bioRxiv preprint reports that an antisense oligonucleotide targeting expanded human ATN1 improved seizure-related outcomes in a humanized mouse model of DRPLA. The findings come from mice, not a human treatment study.
health
A bioRxiv preprint links NR2F1-related changes in retinoic-acid signalling in mouse retinas with foveal abnormalities seen on OCT in people with BBSOAS. The findings point to a retinal component of the syndrome’s visual pathology.
health
A genome-wide association study involving more than one million people examined how genetic variation contributes to personality traits and may influence physical health, mental health and behaviour. The findings highlight genetic effects without separating them from the role of environment.