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Infectious Diseases

Recent reporting, analysis and explainers from the Infectious Diseases desk.

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Complement engineering altered HSV-1 antibody protection in neonatal mice

A bioRxiv preprint reports that mutations tuning complement activity changed how selected monoclonal antibodies protected neonatal mice from lethal HSV-1 infection. The effects varied with the antibody and its viral target.

2026-10-24T18:56:10+05:30
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SLR14 shows antiviral effects against five RNA viruses in preclinical tests

A bioRxiv preprint reports that the RIG-I agonist SLR14 reduced infection or viral replication in human-derived cells and improved outcomes in infected mice. The findings come from cell and animal experiments, not human treatment studies.

2026-10-11T05:53:16+05:30
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