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Chiral graphene quantum dots show antiviral activity in preclinical study

A bioRxiv preprint reports that D-handed histidine-functionalised graphene quantum dots preferentially disrupt virus-associated membrane structures. The work describes antiviral activity in laboratory experiments and protection in mice challenged with human coronavirus OC43.

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Cell study links mitochondrial stress to neuronal death in Chandipura virus infection

A bioRxiv preprint reports that Chandipura virus infection in neuronal cells involves a shift from weakened antiviral signalling to mitochondrial stress, STING activation and GSDME-linked inflammatory cell death. Experiments targeting STING or GSDME altered neuronal injury, with different effects on viral replication.