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Khabre desk
Recent reporting, analysis and explainers from the Cancer Research desk.
health
A 12-patient preprint reports that duplex sequencing detected the aristolochic acid-associated SBS22a mutation signature in blood and urine from patients with signature-positive urothelial tumours. The findings are a proof of concept, not yet a validated population screening test.
health
A medRxiv preprint reports that a risk score based on 28 gut microbial species was associated with cancer diagnoses during up to 10 years of follow-up. The finding comes from an observational analysis and represents a candidate biomarker for future validation, not a clinical screening test.