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Khabre desk
Recent reporting, analysis and explainers from the Bioengineering desk.
science
A bioRxiv preprint describes a method combining extrusion-based 3D bioprinting with multi-pillar anchors to guide skeletal muscle fibre orientation. The researchers report engineered tissues with four architectures and a multi-tissue system modelled on facial musculature.
science
A bioRxiv preprint describes a sequence-design model that encodes preferred protonation states to create pH-sensitive PD-L1 binders. Yeast-display screens recovered hundreds of candidate designs with transition pH values from 4.0 to 5.8.
science
A Stanford team reports that electrostatic charge screening, rather than target-triggered DNA shape changes, dominates the signal in a benchmark aminoglycoside electrochemical sensor. The findings are from a bioRxiv preprint and concern this sensor system.
science
A bioRxiv preprint describes Bio-CM2, a miniature mesoscope combining fluorescence and label-free reflectance imaging across a 7.5 × 10 mm² field of view. Demonstrations in worms, zebrafish and mice paired molecular signals with morphology, behaviour and physiology.
science
A bioRxiv preprint describes a hydrogel made from the extracellular matrix produced by Acinetobacter baylyi ADP1. The material can be modified for light-triggered crosslinking and is reported as porous, injectable, cytocompatible and suitable for 3D bioprinting.