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Khabre desk
Recent reporting, analysis and explainers from the Biophysics desk.
science
A bioRxiv preprint introduces fp-SMD, which models the optically trapped bead, linker and biomolecule together. The authors report that it reproduces a cholesterol–β-cyclodextrin rupture-force histogram and captures force-dependent changes in the molecule’s escape route.
science
A Technical University of Munich preprint describes synthetic DNA strands carrying flavin chromophores that generate spin-correlated radical pairs. The system can be manipulated with radiofrequency fields and read using optically detected magnetic resonance, with DNA sequence and structure controlling its response.
science
A bioRxiv preprint reports that a metastable dimeric intermediate helps recombinant spidroin assemble into native-like fibrils in solution. X-ray diffraction showed that drying drives these fibrils toward amyloid-like cross-β structures.
science
A bioRxiv preprint reports that reinforcement learning identified previously unreported ways to initiate reentry in models of excitable tissue. Learned stimulation patterns produced unidirectional propagation in cardiac monolayers, while whole-heart experiments offered preliminary evidence that they can influence early wave propagation.