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Khabre desk
Recent reporting, analysis and explainers from the Genomics desk.
science
A bioRxiv preprint presents Sma3s v3, a scalable workflow for assigning functions to proteins in proteomes, pangenomes and metagenomes. In tests on a Vibrio cholerae pangenome and a metagenomic catalogue, it reported higher annotation coverage than the cited comparator tools.
science
A bioRxiv preprint presents Rsearch, an R package that integrates VSEARCH with visualisation, parameter optimisation and conversion tools for metabarcoding analysis. In a mock-community comparison with DADA2, the two pipelines produced abundance profiles that closely matched the expected composition, with differences in OTU counts and computational performance.
science
A bioRxiv preprint reports that incomplete reference profiles can leave bulk RNA deconvolution targets non-identifiable even when an algorithm returns precise estimates. The authors propose measuring coverage and false-certification risk, and estimate the measurement precision needed for a decisive result in peripheral blood mononuclear cells.