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Serial ALT measurements estimate liver necrosis in mice

A bioRxiv preprint reports that repeated measurements of circulating alanine aminotransferase, combined with time since acetaminophen exposure, estimated liver necrosis in mice. The method could let researchers follow liver injury in the same animals instead of using separate groups at every timepoint.

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BigHeart maps an adult human heart in 3D at 8.01-micron resolution

A bioRxiv preprint presents a continuous three-dimensional structural map of a whole adult human heart at 8.01-micron isotropic voxel size. The dataset brings myocardial structure, electrical conduction tissue, blood vessels, lymphatic collectors and autonomic nerves into one spatial framework.