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Khabre desk
Recent reporting, analysis and explainers from the Computational Biology desk.
science
Biohub, US federal agencies and industry partners announced a combined $1.8 billion commitment to develop open, AI-ready biological data and measurement technologies. The initiative aims to support predictive models of cell behaviour; the announcement describes planned work, not a completed virtual cell.
science
A bioRxiv preprint describes MIMOSA, a framework that guides antibody-generating models using the structure of a known binder interface. The authors report experimentally validated binders against three targets, with hit rates of 20–26%.
science
Apple researchers describe SimpleDesign, a Transformer-based model that jointly generates protein sequences and three-dimensional structures using a single-stage training approach. The system was trained on more than 2 million sequence–structure pairs, but the supplied evidence reports no experimental validation of its designs.