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Researchers build TriComm, a continuous-culture model of plasmid resistance

A bioRxiv preprint describes TriComm, a three-strain microbial community maintained in continuous culture to study plasmid-mediated antimicrobial resistance. The authors report that resistance plasmids protected the community from collapse under antimicrobial treatment, with protection depending on plasmid transfer.

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Screen links ibuprofen to ciprofloxacin tolerance in C. jejuni

A bioRxiv preprint reports that ibuprofen increased ciprofloxacin tolerance in Campylobacter jejuni in a screen of 2,415 small molecules. The same study identified human-targeted drugs that inhibited the bacterium while sparing commensal microbes.