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Khabre desk
Recent reporting, analysis and explainers from the Neurodegeneration desk.
science
A bioRxiv preprint reports that ALS- and FTD-linked TDP-43 alterations reduce HSV-1 infection in experimental models. The researchers connect the effect to changes in cell-adhesion signalling involving focal adhesion kinase.
science
Researchers mapped 4,321 microproteins in 608 post-mortem human brain samples, including dozens with altered expression in Alzheimer’s disease. The atlas expands the molecular inventory available for studying neurodegeneration, while the proteins’ biological roles still require experimental validation.